Guide to Fluorine NMR for Organic Chemists (Relié)

Following its successful first edition, Guide to Fluorine NMR for Organic Chemists provid an unparalleled guide to fluorine NMR and the impact of fluorine substituents on proton, and carbon NMR spectra. The author enhances each chapter with additional data and updated discussion of recent findings to continue helping working chemists overcome the challenges associated with the synthetic methodologies of fluorinated compounds.
After a thorough introduction of fluorinated compounds, chapters in the text cover : an overview of fluorine NMR, the single fluorine substituent, the CF2 group, the trifluoromethyl group, more heavily fluorinated compounds, compounds and substituents with fluorine directly bound to heteroatoms. Coverage ranges from those compounds containing only a few fluorinated substituents, typically employed in pharmaceutical and agricultural applications, to more heavily fluorinated compounds.
Furthermore, the second edition features new discussion of nitrogen NMR and the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants. Overall, this information enables the effective use of these increasingly popular spectroscopic techniques to accurately characterize compounds that contain fluorine. Featuring NMR data for more than 1,000 specific compounds and including more than 100 exemplary spectra, Guide to Fluorine NMR for Organic Chemists gives the working chemist and advanced student an essential tool for understanding cutting-edge NMR techniques and interpreting the resulting spectroscopic data.