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Despite dramatic advances in neuroimaging techniques, patient-based analyses of brain disorders continue to offer important insights into the functioning of the normal brain. Bridging the gap between thé work of neurologiste studying clinical disorders and neuroscientists studylng the neural mechanisms underlying normal cognition, this book reviews classical neurobehavioral syndromes from both neurological and cognitive scientific perspectives. The contributors are all practlcing neurologiste who also conduct cognitive neuroscience research. Each chapter begins with a case study, describing the patient's symptoms and the cognitive processes involved. The clinical descriptions are followed by historical background on the neurobehavioral syndromes and discussion of the methods used to understand thé underlying neural mechanisms. In their attempts to reconcile confllcting data derived from différent methodologles, many of the authors shed new light on the cognitive mechanisms they discuss. The syndromes include neglect, Balint's syndrome, amnesia, semantic dementia, topographical disorientation, acquired dyslexie, acalculia, transcortical motor aphasia, Wernicke aphasia, apraxia, and lateral prefrontal syndrome.
Mark D'Esposito, MD, is Professor of Neuroscience and Psychology and Director of the Henry H Wheeler, Jr, Brain Imaging Center at the University of Californie, Berkeley.
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